As dental professionals, we can see a smile or a laugh and subconsciously complete a clinical exam and hone into potential problems. The mouth is the “mirror” of the body’s health.1

Research, select associations and institutes have embraced the relationship of the oral-systemic link and recognized the need for the library of information that saliva can provide, to be accessed to move beyond risk assessment, and advance towards detection of oral and systemic diseases. Evolving from the laboratories into clinical settings is the next step for salivary diagnostics.


First and foremost, without the National Institutes of Health (NIH), in collaboration with the National Institute of Dental and Craniofacial Research (NIDCR), saliva may still only be significant during its absence. Additionally, because of these foundations, the pioneers of salivary diagnostics were given a chance to demonstrate the potential saliva has to inform us about complete human health. These pioneers include David T.W. Wong, D.M.D., D.M. Sc, Daniel Malamud, Ph.D., MA and Eric Anslyn, Ph.D., to name a few.2

Salivary diagnostics developed from the study of the “omic” technologies which include: genomics, epigenomics, transcriptomics, proteomics, and metabolomics. Each omic has their own-cataloged library available for free access online.3

This content is restricted. Please contact the American Orthodontic Society to obtain access 1-972-234-4000 Already a member? Click here to login

American Orthodontic Society


Your email address will not be published. Required fields are marked *